DDT and its metabolites in breast milk from the Madeira River basin in the Amazon, Brazil.
نویسندگان
چکیده
Until the 1990s the 1,1,1-trichloro-bis-2,2'-(4chlorophenyl) ethane (DDT) was sprayed in the walls of the house along the Madeira River basin, Brazilian Amazon, a region well known for its large number of malaria cases. In 1910, Oswaldo Cruz described the presence of malaria in 100% of the population living in some localities from the Madeira River basin. Data available in the literature point to the DDT contamination in fishes captured in Madeira River region. Fish is the major source of dietary protein to these people. DDT tends to accumulate in lipid rich tissues and is being eliminated by different events, including lactation. Considering the importance of feeding breast milk to the children, the associated risks of DDT exposure via breast milk intake to children must be assessed. This is the main objective of this work: to analyse the presence of the p,p'-DDT and its metabolites p,p'-DDE and p,p'-DDD in 69 human milk samples and to estimate the intake of DDT and its metabolite in terms of total DDT (total DDT=p,p'-DDE+p,p'-DDD+p,p'-DDT). All the samples showed contamination with DDT and its metabolites ranging from 25.4 to 9361.9 ng of total DDT/g of lipid (median=369.6 ng of total DDT/g of lipid) and 8.7% of the estimated daily intake (EDI), in terms of total DDT, which was higher than the acceptable daily intake proposed by the WHO.
منابع مشابه
Mercury in Amazonian fish from Madeira River basin, Rondônia State, Brazil
This investigation was carried out at the Madeira River basin, located in the state of Rondônia, Brazilian Amazon. Fish from Madeira, Jaciparaná, and Jamari rivers between 7 and 11° parallels south and between 62 and 65° meridians west in Rondônia state, Brazil, were sampled and chemically analyzed for mercury in order to evaluate if the inputs of this metal into the food-chain is occurring in ...
متن کاملLate quaternary dynamics in the Madeira River basin, southern Amazonia (Brazil), as revealed by paleomorphological analysis.
Ancient drainage systems are being increasingly documented in the Amazon basin and their characterization is crucial for reconstructing fluvial evolution in this area. Fluvial morphologies, including elongate belts, are well preserved along the Madeira River. Digital Elevation Model from the Shuttle Radar Topography Mission favored the detection of these features even where they are covered by ...
متن کاملPotamotrygon limai, sp. nov., a new species of freshwater stingray from the upper Madeira River system, Amazon basin (Chondrichthyes: Potamotrygonidae).
Potamotrygon limai, sp. nov., is described from the Jamari River, upper Madeira River system (Amazon basin), state of Rondônia, Brazil. This new species differs from congeners by presenting unique polygonal or concentric patterns formed by small whitish spots better defined over the posterior disc and tail-base regions. Potamotrygon limai, sp. nov., can be further distinguished from congeners i...
متن کاملارزیابی ریسک سرطان زایی و غیرسرطان زایی باقیمانده DDT و متابولیت‌های آن در شیر پاستوریزه در جمعیت عمومی شهر تهران
Background and Objective: Organochlorine pesticides are among the endocrine disrupting chemicals believed to produce a wide variety of adverse health outcomes such as cancers. Generally, fatty foods of animal origin are the major sources of human exposure to lipophilic contaminants such as DDTs and their metabolites. The objectives of the present study were to evaluate exposure of general popul...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemosphere
دوره 73 1 Suppl شماره
صفحات -
تاریخ انتشار 2008